http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105497887-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5256 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-14043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-14021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16134 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-145 |
filingDate | 2015-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105497887-B |
titleOfInvention | A kind of auxiliary agent and its preparation method and application improving the heterologous protection of inactivated avian influenza vaccine |
abstract | The invention discloses a kind of auxiliary agents and its preparation method and application for improving the heterologous protection of inactivated avian influenza vaccine, belong to field of biotechnology.Auxiliary agent of the present invention is that the recombinant baculovirus of avian influenza virus conservative antigen epitope can be expressed in vertebrate body using baculoviral as carrier.Avian influenza virus quickly makes a variation; and existing inactivated avian influenza vaccine is weak to heterologous strain protection; the rod-shaped viral genome of encoding gene insertion of avian influenza virus is highly conserved antigen fragment HA2 76-130 with cross-protection of the present invention, 3M2e, NP55-69, NP380-393; it is prepared into the inactivated avian influenza vaccine auxiliary agent being immunized through intramuscular injection, is used in combination with inactivated vaccine.The auxiliary agent overcomes traditional inactivated avian influenza vaccine to the deficiency in terms of heterologous strain cross-protection, to realize to the effective prevention and control of bird flu epidemic situation. |
priorityDate | 2015-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.