http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105496949-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62a71b5ba45255cc0ee9ab38237e3a20 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5383 |
| filingDate | 2015-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_473d1fedfa15e3c9cf07e0316d0b33b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8a1651882315d701dc0456afdf3d784 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0568ad5391ebfec8510de15abe771d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0794d9912b68a08238b4af3426700d9d |
| publicationDate | 2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105496949-A |
| titleOfInvention | Preparation method of slow-released levofloxacin injection |
| abstract | The invention provides a preparation method of a slow-released levofloxacin injection, and belongs to a slow-released injection for animals. The levofloxacin injection is prepared from, by weight, 5%-20% of levofloxacin, 1%-4% of fatty acid, 5%-35% of stabilizer and the balance organic solvent. The preparation method comprises the steps that levofloxacin and the organic solvent are taken and stirred for dissolution, the fatty acid is added to conduct a complexation reaction with a dissolved product, the stabilizer is added, after sufficient dissolution is achieved, the organic solvent is added for the scale volume, and the slow-released levofloxacin injection is obtained after membrane filtration is conducted. According to the preparation method of the slow-released levofloxacin injection, levofloxacin or a salt hydrate thereof is reacted with the fatty acid to form a new compound, the release time of levofloxacin can be prolonged, the effective blood drug concentration of a drug in an animal body can be maintained for a long time, and therefore the purposes of decreasing the frequency of drug delivery and reducing drug stress are achieved. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108567761-A |
| priorityDate | 2015-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.