http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105481972-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2016-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105481972-B |
| titleOfInvention | A kind of pair of nerve cell protein expression has the polypeptide and its preparation method and application of adjustment effect |
| abstract | The invention discloses the polypeptides and its preparation method and application that a kind of pair of nerve cell protein expression has adjustment effect.Polypeptide provided by the invention has 155-194 amino acids sequence shown in SEQ ID NO:1.Preparation method of the present invention is that the DNA molecular for obtaining encoding active polypeptide by rite-directed mutagenesis is merged with expression vector, constructs recombinant expression carrier transfection host cell, inducing expression fusion protein isolates and purifies the fusion protein of expression.The present invention also provides application of the polypeptide in the regulation of nerve cell protein expression and the applications in adjusting nerve synapse structure and function.Peptide molecule announced through the invention can targetedly regulatory protein express, to influence nerve synapse function, present invention can apply to the exploitations of the investigational agent of a variety of the nervous system diseases and therapeutic agent. |
| priorityDate | 2016-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.