Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1131 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
filingDate |
2014-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2020-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-105473717-B |
titleOfInvention |
Antisense Oligonucleotide Compositions |
abstract |
The present invention relates to antisense oligonucleotide (ASO) compositions, and in particular to compositions and methods for cytoplasmic delivery of antisense oligonucleotides (ASO). A partially single-stranded and partially double-stranded hybrid ASO is provided that hybridizes to form a double-stranded region that can non-covalently bond to the nucleic acid binding protein region. In this way, ASO::protein complexes can be produced that facilitate delivery of antisense DNA into target cells. Such complexes can be used to downregulate gene expression in cells. |
priorityDate |
2013-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |