abstract |
The present invention provides the discovery of the role of EphA4 signaling in neurodegenerative disorders involving β-amyloid-induced neurotoxicity, such as Alzheimer's? Disease. Novel therapeutic methods, therapeutic agents, and kits for treating diseases caused or aggravated by overactivated EphA4 signaling are provided. Also provided are methods for identifying overactive EphA4 as may be involved in treatments. |