http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105461642-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 |
filingDate | 2015-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105461642-B |
titleOfInvention | Novel quinazoline derivative LU1505 as well as preparation method and application thereof |
abstract | The invention discloses a novel quinazoline derivative LU1505 and a preparation method thereof. The novel quinazoline derivative LU1505 is chemically named as N-[[(4-dimethylamino) phenyl]methyl]-4-N-[7-methoxy-6-(2-pyrrolidine-1-yl) hydroxyethyl] quinazoline-4-yl] benzene-1,4-diamine. The quinazoline derivative as well as pharmaceutically acceptable salts, solvates and hydrates thereof has excellent anti-tumor in-vivo and in-vitro activity for MCF-7, SK-BR-3, A172, HCT116, U-118MG, U-87MG and MDA-MB-468 and has better application prospect in preparation of antitumor drugs. |
priorityDate | 2015-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.