| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5cf30792dbad75d7c1c782405a527910 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2015-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a2d8db8b59b9efb1e19d610b676ea96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_760f8d968f6867e1faab6ddb5e468a6c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0bcb56ed46e2261aa337214da61a474
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b4ed825bcf3a9603ecd848a497cdfef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05bca16e6c343a8e39779d07ad542e06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_857334e762a3834e162a7bec123d3c00 |
| publicationDate |
2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-105441550-A |
| titleOfInvention |
Early biomarker for auxiliary diagnosis of acute ischemic stroke, and gene chip and real-time fluorescent quantitative PCR (polymerase chain reaction) evaluation methods of early biomarker |
| abstract |
The invention discloses an early biomarker for auxiliary diagnosis of acute ischemic stroke, which is microRNA-27a-3p in plasma. The invention also discloses a gene chip evaluation method and a real-time fluorescent quantitative PCR (polymerase chain reaction) evaluation method of the plasma microRNA-27a-3p serving as the early biomarker for auxiliary diagnosis of the acute ischemic stroke. By adopting combination of a gene chip and a real-time quantitative PCR technology, a differential expression of the plasma microRNA-27a-3p is discovered. On the basis of the differential expression, the diagnostic efficiency of the microRNA-27a-3p for the acute ischemic stroke is investigated. An experimental result shows that the expression level of the plasma microRNA-27a-3p in plasma of an acute ischemic stroke patient is significantly lower than that in a healthy person, and a critical value and the sensitivity and specificity of the microRNA-27a-3p for auxiliary diagnosis of the acute ischemic stroke patient are preliminarily determined. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112599237-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114752669-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112599237-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106337089-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114015759-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114231615-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114231615-B |
| priorityDate |
2015-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |