http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105441062-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-68 |
| filingDate | 2014-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105441062-B |
| titleOfInvention | A kind of fluorescence probe substrate of people's enteron aisle Carboxylesterase Activity detection and its application |
| abstract | A kind of fluorescence probe substrate of people's enteron aisle Carboxylesterase Activity detection and its application belong to pharmaceutical technology field.The Specific probe is (E) 2 (4 (4 hydroxyl vinylbenzyl) 3 cyano group 5,5 dimethyl furan 2 (5H) subunits) malononitrile (being abbreviated as TCF) aromatic ester (being abbreviated as TCFE), the substrate can be used as people's enteron aisle Carboxylesterase Activity Quantitative detection, and the quick screening and assessment of people's enteron aisle carboxylesterase inhibitor.People's enteron aisle Carboxylesterase Activity Quantitative detection flow is as follows：It is probe reaction to select TCFE hydrolysis, suitable substrate is added in the buffer solution system containing hCE2, the Actual activity of hCE2 enzymes in various external biological samples is determined by the growing amount of its hydrolysis metabolite TCF in the quantitative detection unit interval in linear reaction interval.The probe is with good selectivity and hydrolysate TCF is with longer fluorescence emission wavelengths (612nm), can reduce biological specimen itself background fluorescence, strengthen sensitivity, have good practicality and application prospect. |
| priorityDate | 2014-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 333.