http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105440094-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30596b14b4a92ca1018c1166af4f0031 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-002 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 2015-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ac0c1cfea0482b0eb296a7bfa455ddc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4e758627cb716f29d0fd7c4ad3b49cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bbd5fa921b784ce45b432fea3f7f5a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7d6f60572295a5933d3f9ca03673818 |
| publicationDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105440094-A |
| titleOfInvention | The preparation method of dexamethasone intermediate |
| abstract | The invention discloses a preparation method of a dexamethasone intermediate, which uses the compound 17β-cyano-17α-hydroxyandrost-4,9-dien-3-one as the starting material, and passes through the 3-ketone carbonyl Protection reaction, 17-hydroxyl protection reaction, Grignard reaction, 3-ketone carbonyl deprotection reaction, dehydration reaction, dehydrogenation reaction to obtain methyl tetraene (5-ST). The starting material 17β-cyano-17α-hydroxyandrost-4,9-dien-3-one of the present invention is rich in sources, low in price, novel in process route design, small in impact on the environment in the production process, and high in overall yield , has high competitiveness and is suitable for industrial production. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107286215-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107698644-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107698644-A |
| priorityDate | 2015-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.