http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105440057-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12 |
| filingDate | 2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105440057-B |
| titleOfInvention | A kind of method for preparing cefoperazone sodium |
| abstract | The present invention discloses a kind of method for preparing cefoperazone sodium, including：Dissolving：Acetone and purified water are added into retort, stirring is opened, cefoperazone acid is added, pH6.8~7.2 are adjusted, cefoperazone acid is dissolved complete；Decolourize：Cefoperazone acid solution is added into activated carbon decolorizing, then successively by decarburizing filter, multistage degerming filter core, is pressed into desinfection chamber crystallizing tank；Crystallization：Stream plus organic solvent, crystallization into crystallizing tank；The lower growing the grain of stirring, three-in-one filter filtering, filter cake is washed with acetone；Dry：Filter cake after washing enters drying equipment, methanol Jing Guo aseptic filtration, water or methanol-water are atomized by direct-injection type atomising device, driven with sterile nitrogen after gas purges 2 ± 1.5h to filter cake after atomization and open hot water circuit heat supply again, be dried under vacuum to the qualified rear discharging of dissolvent residual.Acetone residue is much smaller than 0.5% in the cefoperazone sodium product that the present invention is obtained, and improves product quality and stability, medication is safer, produces good social benefit. |
| priorityDate | 2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.