http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105440054-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-28 |
| filingDate | 2015-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105440054-B |
| titleOfInvention | A kind of technique preparing cefathiamidine |
| abstract | The present invention relates to a kind of techniques preparing cefathiamidine, more particularly to a kind of technique preparing high-purity cefathiamidine.Preparation method is：Preparation method is：In acetyl bromide 7ACA and N, in the reaction of N ' di-isopropyl thioureas or after reaction, the inorganic salt solution of water or water is added as secondary solvent；After reaction, cooling, dropwise addition crystallization solvent, suction filtration obtain cefathiamidine crude product；High-purity cefathiamidine is obtained after purifying vacuum drying again.Preparation method through the invention, the residual of impurity in cefathiamidine can be effectively reduced, and the content of acetyl bromide 7ACA and high-molecular compound impurity can be made to be reduced to 0.1% or less or fully erased, the residual of other cefathiamidine impurity can be reduced to 0.2% or less. |
| priorityDate | 2015-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.