http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105439974-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06 |
| filingDate | 2014-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105439974-B |
| titleOfInvention | A kind of preparation method of lipase inhibitor |
| abstract | The invention belongs to pharmaceutical technology field; more particularly to the methyl 4H 3 of 2 hexadecane epoxide of lipase inhibitor 6; the preparation method of the ketone of 1 benzoxazine 4; the present invention passes through the methyl benzoyl carbamate formula (II) of 2 halo of intermediate cetyl 5; under catalyst action; 1 (2 halogenophenyl) 1 is prepared by the halo benzamide cyclization rearrangement reaction of N acyl groups 2; 3 diketone; lactams four-membered ring is initially formed by NH in acid imide and halogen dehydrohalogenation, then forms the ketone structure of benzoxazine 4 through C N rearrangement reactions.The present invention has the characteristics of product purity is high, simple for process and safe, suitable industrialization production requirements. |
| priorityDate | 2014-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 130.