http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105435311-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3852 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3847 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3817 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3821 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-46 |
| filingDate | 2015-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105435311-B |
| titleOfInvention | A kind of tissue engineered bone cartilage compound rest and preparation method thereof |
| abstract | The invention discloses a kind of tissue engineered bone cartilage compound rest and preparation method thereof, belong to technical field of biological materials.The stent is multiple integral structure, is made of cartilage tissue scaffold layer, cartilaginous tissue calcified layer, porous cell separation film and tissue scaffold design layer.Cartilage tissue scaffold layer is inoculated with cartilage cell and introduces the growth factor promoted into cartilage, promotes the growth of cartilage cell；The primary raw material such as good biocompatibility and degradable heparin sulfate proteoglycans is selected, the functionalization multiple integral tissue engineered bone cartilage compound rest of good mechanical properties is obtained using the methods of cross-linking reaction, freeze-drying, orientation pore-creating, MULTILAYER COMPOSITE, fully integratedization.The present invention uses hydroxyapatite crystal and degradable non-stoichiometric polyethylene glycol/coaxial staple fiber of poly epsilon caprolactone lactone nanometer and the heparin sulfate proteoglycans/oxidized sodium alginate for being grafted RGD and N succinyl-chitosans for composite, is mainly used for the reparation of articular cartilage and subchondral bone full-thickness defects. |
| priorityDate | 2015-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.