abstract |
The invention relates in part to nucleic acids encoding proteins; nucleic acids containing non-canonical nucleotides; therapeutic agents comprising nucleic acids; methods, kits and devices for inducing cells to express proteins; Methods, kits, and devices; and cells, organisms, and therapeutics produced using these methods, kits, and devices. Disclosed herein are methods of using RNA for inducing cells to express proteins and for reprogramming and gene editing cells. Also disclosed are methods for producing cells from patient samples, cells produced using these methods, and therapeutic agents comprising cells produced using these methods. |