http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105418517-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 |
filingDate | 2015-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105418517-B |
titleOfInvention | Novel quinazoline derivative LU1509 as well as preparation method and application thereof |
abstract | The invention discloses a novel quinazoline derivative LU1509 as well as a preparation method and application thereof. The novel quinazoline derivative is chemically named as N-4-[(4-dimethylaminophenyl)methoxy]phenyl-7-methoxy-6-[(2-pyrrolidin-1-yl)hydroxyethyl]quinazolin-4-amine. The quinazoline derivative as well as pharmaceutically acceptable salt, solvate and hydrate thereof have excellent in vitro and in vivo anti-tumor activities to MCF-7, SK-BR-3, A549, HCT 116, MDA-MB-468 and have relatively good application prospects in the preparation of anti-tumor drugs. |
priorityDate | 2015-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.