http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105399791-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 2015-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105399791-B |
| titleOfInvention | A kind of preparation method of betamethasone intermediate |
| abstract | The present invention relates to a kind of preparation method of Steroid medicine intermediates; specifically related to a kind of betamethasone intermediate; that is 16 β methyl, 17 α monohydric pregnants 4; 9 diene 3; the preparation method of 20 diketone; it is obtained target product through cyanogenation, ketal protection reaction, double elimination, epoxy reaction and grignard addition hydrolysis by pregnant 3,17 diketone of steroid of 9 α hydroxyls, 4 alkene.The invention provides preparation process in the middle of a kind of brand-new betamethasone for being more suitable for producing, cheap and easy to get with initiation material, each step operation is simple, the characteristics of high income, is adapted to industrialized great production, and its yield and quality can reach satisfied level. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108033990-A |
| priorityDate | 2015-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.