http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105384815-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
filingDate | 2015-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105384815-B |
titleOfInvention | A kind of scFv antibody is treating or preventing the application in Bursal Disease preparation |
abstract | The invention discloses a kind of scFv antibody to treat or prevent the application in Bursal Disease preparation in preparation.ScFv-GD antibody provided by the invention, including being made of heavy chain variable region, light chain variable region and the bonding pad between them;Heavy chain variable region is for following (a) or (b) :(a) the protein being made of 1 1-128 amino acids residue of sequence;(b) (a) by the substitution and/or deletion and/or addition of amino acid residue and had into identical active protein;Light chain variable region is for following (c) or (d): the protein that (c) is made of 1 144-249 amino acids residue of sequence;(d) (c) by the substitution and/or deletion and/or addition of amino acid residue and had into identical active protein.The scFv-GD antibody that invention provides, it is to be obtained using the bacteria display technology screening of Ag-Ab coexpression, the neutralization activity of the scFv-GD antibody has many advantages, such as that high specificity, therapeutic effect are more preferable than high 10 times of scFv-A antibody or more that have awarded patent right. |
priorityDate | 2015-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 362.