http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105384734-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 |
| filingDate | 2015-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105384734-B |
| titleOfInvention | Trinitrogenazole alcohol antifungal compound and the preparation method and application thereof with the side chain of oxadiazoles containing piperidines |
| abstract | The present invention relates to pharmaceutical technology fields, the present invention provides 1 (1H 1 of one kind, 2,4 triazole, 1 base) 2 (2,4 difluorophenyls) 3 ((substitution of piperidines oxadiazoles side chain)) 2 propanol compounds, any mixture including its cis-trans-isomer and its these form or its pharmaceutical salts, shown in the chemical constitution such as formula (I) of the compound.The present invention also provides the preparation methods of above compound, and the application in preparing antifungal drug.The compounds of this invention is found through antimycotic experiment, there is very strong anti-mycotic efficiency to various superficial parts and deep fungal, compared with the antifungal drug of existing clinical application such as Fluconazole, have the advantages that efficient, toxicity is low, antimycotic spectrum width, and there is preferably activity to fluconazole resistant, can be used for preparing new antifungal drug. |
| priorityDate | 2014-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 148.