abstract |
The present invention relates to compounds of the following formula (I) wherein: -R 1 is H or OH, -R 2 is (C 1 -C 6 ) alkyl, COOH, COO-((C 1 -C 6 ) alkyl) or thiazole group, -R 3 is H or (C 1 -C 6 ) alkyl, and -R 4 is aryl -(C 1 -C 6 ) substituted by one or more groups selected from OH and NR 9 R 10 groups C 8 ) alkyl, or a pharmaceutically acceptable salt, hydrate or solvate thereof, and uses thereof, especially for treating cancer, a pharmaceutical composition containing the same, and a preparation method thereof. |