http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105367674-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 |
| filingDate | 2014-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105367674-B |
| titleOfInvention | It a kind of bacillus calmette-guerin polysaccharide and its prepares and analyzes and identifies method |
| abstract | The invention discloses a kind of bacillus calmette-guerin polysaccharide and its prepares and analyze and identify method.Using BCG polysaccharide nucleic acid as raw material, the physical chemical differences according to polysaccharide and nucleic acid are eluted using 32 cellulose chromatography columns of DEAE by eluant, eluent of deionized water, collect eluent, and desalination of dialysing, it is 1.78 × 10 that concentrated frozen, which is dried to obtain molecular weight, 4 The bacillus calmette-guerin polysaccharide of Da.Bacillus calmette-guerin polysaccharide passes through complete sour water solution, it methylates and combines GC MS, IR, NMR identifies the polysaccharide using (1 → 4) α D Glcp as main chain, containing it is a small amount of → 4,6) (glucan of 1 → branch, average every 8 main chain saccharide residues contain 1 branch to α D Glcp, and have main chain C6 to have deoxidation methyl bimodal.The present invention by it is a kind of be simple and efficient, the method without destruction, isolate and purify to obtain bacillus calmette-guerin polysaccharide, product purity is high；Structural characterization is carried out to the polysaccharide, is of great significance to the active ingredient and structure activity study of clear BCG vaccine polysaccharide. |
| priorityDate | 2014-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.