http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105358189-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82B1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-46 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-44 |
| filingDate | 2014-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105358189-B |
| titleOfInvention | Bionical collagen hydroxyapatite composite material |
| abstract | The present invention relates to：A kind of bionical collagen hydroxyapatite composite material, it includes at least part fibrosis collagen scaffold, the support includes the ripe native collagen fibers for possessing the triple helices as shown in circular dichroism, wherein, the crystal of those ripe native collagen fibers at least partly nanometer crystal hydroxylapatite covered with epitaxial growth, thus the nanocrystal of the epitaxial growth have with people's bone mineral identical pattern and with people's bone mineral identical size, i.e., 30~50nm length and 14~25nm width, the preparation method of above-mentioned bionical collagen hydroxyapatite composite material, it the described method comprises the following steps：A) at least part fibrosis collagen scaffold comprising above-mentioned ripe native collagen fibers is immersed into saturation Ca 2+ /H x PO 4 (3‑x) Saturated aqueous solution in start the forming process of composite implantation material, thus the nanocrystal of epitaxial growth is formed on the native collagen fibers of maturation, the nanocrystal of the epitaxial growth has and people's bone mineral identical pattern and identical size, b) by the way that solid material is separated with the aqueous solution, cleaned and dried with water and stop the forming process of the composite implantation material, and c) alternatively the material of the separation from step b) is carried out disinfection, and above-mentioned bionical collagen hydroxyapatite composite material is used for the bon e formation of the defects of human subjects or animal opening position as implant or prosthese, osteanagenesis, Bone Defect Repari and/or bone displacement or the application for being used for bone and synchondrosis regeneration as implant. |
| priorityDate | 2013-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.