| abstract |
The present invention relates to a kind of synthetic method of carbonyl alcohol compound shown in following formula (II), described method comprises: in organic solvent, in the presence of catalyst, silver trifluoroacetate and auxiliary agent, following formula (I) compound and Hydroxylamine hydrochloride reacts, and through aftertreatment after reaction finishes, thereby obtain described formula (II) compound, Wherein, R 1 is selected from H, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, halogen or nitro; R 2 and R 3 are each independently C 1 -C 6 alkyl. The method obtains the target product with a high yield through the mutual promotion and synergy of the catalyst, the auxiliary agent, the organic solvent and the silver trifluoroacetate, and has good application prospects and industrial production potential in the technical field of organic synthesis. |