http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105344128-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5adbc1fa5f102bef8900e78f16bf1c9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2221-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2011-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2259-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D2251-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D11-0203 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D11-02 |
| filingDate | 2015-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ea074e5be70a4361115793a0b878c63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eee4160719fcaad927f02cc6bc5ca564 |
| publicationDate | 2016-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105344128-A |
| titleOfInvention | Method for removing organic solvent residue from bulk drug |
| abstract | The invention discloses a method for removing organic solvent residue from a bulk drug. The method includes: under a temperature of 35-80DEG C and a pressure of 10-40MPa, firstly performing static extraction for 0.5-2h, and then conducting dynamic extraction for 0.5-6h so as to obtain a bulk drug finished product with the organic solvent residue meeting the limit standard in an extraction kettle; carrying out pressure reduction separation on the carbon dioxide flowing out of the extraction kettle at a pressure of 4-7MPa and a temperature of 25-45DEG C, collecting the precipitate in a separation kettle, recovering the bulk drug, and loading the bulk drug into the extraction kettle for application. An adsorbent is employed to conduct adsorption separation on the carbon dioxide flowing out of the separation kettle, and the obtained carbon dioxide is introduced into the extraction kettle for cycle use. The bulk drug finished product obtained by the method has the organic solvent residue meeting the limit standard, the bulk drug yield is high, and the carbon dioxide can be recycled. The method provided by the invention has the advantages of simple process, stable operation, economical efficiency and high efficiency, and is suitable for industrial application. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108392849-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108176077-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109200621-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108176077-B |
| priorityDate | 2015-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 167.