http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105343031-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
| filingDate | 2015-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105343031-B |
| titleOfInvention | A kind of ivermectin solid lipid nano granule and preparation method thereof |
| abstract | The invention discloses a kind of ivermectin solid lipid nano granules, it includes the component of following parts by weight：0.75~3 part of 0.03~1 part of ivermectin, 5 parts of palmitic acid, 1~5 part of ten polyglycereol monolaurate and polyvinyl alcohol.Compared with prior art, ivermectin solid lipid nano granule produced by the present invention, for grain size between 230~350nm, potential value is preferable, polydispersity index<0.25, it is redissolved after freeze-drying, grain size, current potential are almost unchanged, can be preserved for a long time after freeze-drying.Electronic Speculum observes blank nanoparticle and drug-carrying nanometer particle in regular oblong, envelop rate, drugloading rate 0~12.9%.Meanwhile the Solid lipid of the invention screened and surfactant are biodegradable material, toxicity is low, has no stimulation of the skin；Matrix material used in the present invention can embedding medicinal reach the effect of sustained-release and controlled release. |
| priorityDate | 2015-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.