http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105331600-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e12c12d17444f9f8e2d9735ace67488 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2014-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48211deef3cf5a43b8137a4867b6832f |
| publicationDate | 2016-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105331600-A |
| titleOfInvention | Method for noninvasive acquisition of complete genome DNA from fetus |
| abstract | The invention provides a method for noninvasive acquisition of complete genome DNA from a fetus. The method comprises the following steps: isolating karyocyte from the peripheral blood of a parent body (a pregnant woman); preparing a karyocyte smear; comparing and analyzing fetus special or paternal special genetic markers (not existing in a maternal source); synthesizing a fetus special or paternal special genetic marker probe (not existing in the maternal source), and marking fetus karyocyte; micro-dissecting and isolating the marked fetus karyocyte; and conducting high-fidelity whole genome DNA amplification to fetus karyocyte single cells obtained from dissection. The method disclosed by the invention can guarantee precise acquisition of fetus-derived whole genome DNA and can lay a material base for the application to noninvasive prenatal genetic diagnosis, so that the method has a broad application prospect. |
| priorityDate | 2014-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.