http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105330724-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate | 2015-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105330724-B |
| titleOfInvention | A kind of anti-angiogenesis polypeptide [D-Ala1]AS16 |
| abstract | The invention belongs to biopharmaceutical technologies, and in particular to a kind of polypeptide [D-Ala with blood vessel formation against function 1 ]AS16.Contain 16 amino acid, molecular weight 1683.0 in the polypeptide structure, specific amino acid sequence is D-ATWLPPRAANLLMAAS.Compared to existing AS16 polypeptide, show preferably by inhibiting tumor angiogenesis to inhibit the effect of the growth of tumour, and tumor control rate and organism survival phase have also obtained more significantly improving；Long_term toxcity the experimental results showed that, polypeptide [D-Ala provided by the present invention 1 ] AS16 can slow down the body weight increase speed of rat；After convalescence, rat body weight restores normal.Thus in general, polypeptide [D-Ala 1 ] AS16 future tumors therapeutic agent application in show preferably prospect. |
| priorityDate | 2015-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 183.