http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105330588-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105330588-B |
| titleOfInvention | Alkaloid Oleracone and its extraction separation method in purslane |
| abstract | New alkaloids Oleracone and its extraction separation method in purslane, from purslane dries medicinal material, with water boiling and extraction, filtering, merging filtrate, heating concentration；Through macroporous absorbent resin removal of impurities, respectively with water and ethanol gradient elution, ethanol washing lotion is concentrated under reduced pressure；Concentrate is extracted with ethyl acetate again, ethyl acetate is recovered under reduced pressure；It is extract obtained to be separated through silica gel column chromatography, 130 positions are obtained with petroleum ether acetone gradient elution successively, 90 130 position eluates are concentrated under reduced pressure；10 positions are obtained with methanol-water isocratic elution through compression leg in ODS again, position 3 is concentrated under reduced pressure, through Sephadex LH 20 with methanol-water isocratic elution, produce new skeleton alkaloids compound, structural formula is determined through the experiment of wave spectrum analysis, chemical method and X-ray single crystal diffraction, and is named as Oleracone.Using extraction separation method of the present invention prepare purslane new alkaloids Oleracone, can be used as other compound synthesis primers, and new drug development and pharmacology activity research raw material. |
| priorityDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.