| abstract |
The invention discloses a medical purpose of an NMDA acceptor antagonist and a pharmaceutical composition thereof. The invention concretely discloses a medicine for using the NMDA acceptor antagonist, a pharmaceutically acceptable salt or a pharmaceutical composition thereof for treating or preventing central nervous system disease and/or mental diseases, and the NMDA acceptor antagonist is delivered to a human central nervous system through target administration. An application of the pharmaceutical composition can increase the concentration of the NMDA acceptor antagonist in brain tissue, medicine amount is greatly reduced, and systematic side effect is reduced; biology availability in the brain is high, autonomous drug administration can be carried out by patients, no pain is generated, usage is convenient, and thus the pharmaceutical composition has good patient compliance, and has wide clinical medical science application. |