abstract |
The present invention relates to iRNAs such as double-stranded ribonucleic acid (dsRNA), compositions targeting the complement component C5 gene and the use of such iRNAs (eg dsRNA), compositions to inhibit the expression of C5 and to treat patients with a complement component C5-associated A method for a subject with an associated disease (eg, paroxysmal nocturnal hemoglobinuria). |