http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105296507-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-40 |
filingDate | 2015-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105296507-B |
titleOfInvention | Lassa fever virus-like particle, its preparation method and application |
abstract | The invention relates to a Lassa fever virus-like particle, its preparation method and application. The invention connects Lassa fever virus Z, N and GPC genes with insect cell expression vectors respectively, and uses the baculovirus/insect cell expression system to produce Lassa fever virus-like particles. The Lassa fever vaccine is prepared by mixing the Lassa fever virus-like particle with a preservative and an adjuvant. The Lassa fever virus-like particle and the vaccine thereof of the present invention can efficiently induce the body to produce neutralizing antibodies, filling in the blank of such vaccines in China. The preparation method of the invention is suitable for industrial production and has the advantages of low cost, high safety and the like. |
priorityDate | 2015-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 238.