http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105294519-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-59 |
| filingDate | 2015-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105294519-B |
| titleOfInvention | A kind of synthetic method of the moCys fragments of marine natural productss apratoxin E |
| abstract | The present invention relates to a kind of synthetic method of the moCys fragments of marine natural productss apratoxin E, belongs to the field of chemical synthesis.The present invention is with cheap and easily-available L glutamic acid as raw material; the Boc of esterification, amido through acid protects 7 steps such as the allyl etherification reaction of reaction, the Chemoselective reduction of adjacent amido ester, the Mitsunobu cyclizations of adjacent amido alcohol, the acridine ring-opening reaction of triphenyl mercaptan, ester hydrolysis reaction and acid to react, and has synthesized the moCys fragments of marine natural productss apratoxin E（C27 C30 fragments）.The present invention have raw material is cheap and easily-available, total recovery is high, good product selectivity, be adapted to industrialized production the features such as. |
| priorityDate | 2015-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.