http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105294458-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 |
| filingDate | 2015-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105294458-B |
| titleOfInvention | A kind of anti-tumor small molecular compound and its preparation method and application |
| abstract | The invention provides a kind of anti-tumor small molecular compound and its preparation method and application, the compound is 3 (2 (([1,1' biphenyl] 4 methylene) amino) ethyl) phenol, and molecular formula is C 21 H 21 NO, structural formula is： Preparation method is：Using a hydroxyl phenylacetic acid and 4 bromobenzylamine hydrochlorides as raw material, N (4 bromobenzyl) 2 (3 hydroxyphenyl) acetamide is obtained by acylation reaction；Reaction is substituted successively again and reduction reaction obtains the compound.The compound has broad-spectrum anti-tumor activity and good penetrability, can suppress tumor cell proliferation and promote apoptosis of tumor cells, toxic and side effect is small, simple in construction, it is easy to synthesize, and is that good basis and optimistic application prospect have been established in the development of new antineoplastic. |
| priorityDate | 2015-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.