http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105272976-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
| filingDate | 2014-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105272976-B |
| titleOfInvention | Yi Zhong oxazolidinone compounds |
| abstract | The present invention provides oxazolidinone compounds shown in formula I or its pharmaceutically acceptable salts, hydrate or crystal form；Wherein, R is selected from-CH 2 NHR 1 ,-CH 2 R 2 、‑CONHR 3 ；Wherein, R 1 Selected from-COCH 2 CH 3 、‑CHO、‑SO 2 CH 3 、‑SO 2 N(CH 3 ) 2 、‑COOCH 3 、‑CONHCH 2 CH 3 、‑COCH 2 F、‑COCHF 2 Or-COCF 3 ；R 2 Selected from methyl piperazine base, ethyl piperazidine base, hydroxyethyl piperazine base, hydroxyl second methylamino, the third cyanogen methylamino, piperidyl, acetoxymethyl ester piperidyl, hydroxy piperidine base, 4- (4- fluorophenyl) piperidyl, morpholinyl, succimide base, imidazolidinyl diketo, thiazolidinedione base, imidazole radicals, 1,2,3- triazol radical ,-OCOCH 3 、‑OCOC 6 H 5 、‑OCH 3 Or thiophenic sulfur alcohol radical；R 3 Selected from hydrogen atom, methyl, methoxyl group.The present invention also provides the purposes of compound.The present invention has eventually found and safety higher noval chemical compound suitable with existing antimicrobial compound FYL-66 antibacterial activity, has provided better choice for clinical application by largely testing screening. 。 |
| priorityDate | 2014-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 184.