http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105255846-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B09C1-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B09C1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 |
| filingDate | 2015-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105255846-B |
| titleOfInvention | A kind of engineering organophosphor hydrolytic enzyme, nucleic acid and mutant and its application |
| abstract | The present invention relates to a kind of engineering organophosphor hydrolytic enzyme, nucleic acid and mutant and its applications, belong to technical field of bioengineering.Engineering organophosphor hydrolytic enzyme of the invention is one in the 55th, the 57th, the 83rd, the 114th, the 137th, the 188th of the amino acid sequence as shown in SEQ ID No.1 or the 262nd amino acids residue or organophosphor hydrolytic enzyme mutant that the activity of amino acid sequence composition that multidigit is formed after amino acid substitution improves.Compared with prior art, the organophosphor hydrolytic enzyme mutant in the present invention improves 36.7 times to the catalytic activity of malathion, while the mutant maintains maternal excellent thermal stability, and 50 DEG C of half-life period reach 65h.Organophosphor hydrolytic enzyme mutant in the present invention can the common organophosphorus pesticide such as efficient degradation malathion, thermal stability is good, has a good application prospect in degrading organic phosphor pesticides field. |
| priorityDate | 2015-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.