http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105254780-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate | 2015-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105254780-B |
| titleOfInvention | A kind of bionical derivative of cation type chitosan and its application |
| abstract | The present invention discloses a kind of bionical derivative of cation type chitosan and its application, belongs to biological medical polymer material technical field.The bionical derivative of cation type chitosan that the present invention is provided contains：1. there is di(2-ethylhexyl)phosphate choline group (PdC) of the double positive charge structures of local branch, water-soluble improvement, cytotoxicity and blood compatibility can be taken into account, and be conducive to keeping protein conformation；2. the acetyl histidine group with pH sensitiveness, can promote carrier system intracellular lysosome to escape, and collaboration PdC improves the intracellular efficiency of transmission of pharmaceutical grade protein.The derivative can be self-assembly of nano combined system through simple process in a mild condition with pharmaceutical grade protein, show good biocompatibility and enter born of the same parents' efficiency, and can Protein requirement activity, for pharmaceutical grade protein conveying. |
| priorityDate | 2015-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.