http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105254586-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-72 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-72 |
| filingDate | 2015-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105254586-B |
| titleOfInvention | Sulfur heterocyclic ring chalcone derivative and its preparation method and application |
| abstract | The invention discloses class sulfur heterocyclic ring chalcone derivative and its preparation method and application, belong to medicinal chemistry art.The present invention utilizes classical necleophilic reaction to splice thia ring and chalcone parent nucleus skeleton, simple efficient, has synthesized to environmental protection sulfur heterocyclic ring chalcone derivative.It has following general structure： R 1 It is 2 benzothiazolyls, 2 thiazolinyls, 2 thiadiazolyl groups, 2 pyrimidine radicals；R 2 It is 3,4,5 trimethoxies or diverse location is monosubstituted or disubstituted on phenyl ring for fluorine, chlorine, bromine.The experiment of such Compound ira vitro antibacterial activity shows there is certain inhibitory activity to staphylococcus aureus, Escherichia coli, stenotrophomonas maltophilia and Candida albicans, especially there is strong inhibitory activity to Escherichia coli, can be applied to prepare antibacterials as the candidate of further exploitation or lead compound. |
| priorityDate | 2015-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.