http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105247076-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-686 |
filingDate | 2014-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105247076-B |
titleOfInvention | Methods of Amplifying Fragmented Target Nucleic Acids Using Assembled Sequences |
abstract | The present invention provides methods of amplifying a fragmented target nucleic acid containing short target nucleic acid fragments, using an assembly sequence to convert these short fragments into longer sequences, thereby identifying and detecting these sequences. This is especially important when trying to identify small genetic variations, such as SNVs, in highly fragmented nucleic acid samples. Amplification is accompanied by hybridization of the short target nucleic acid sequences to the assembly sequences, these short sequences serving as primers for extension. Since the target nucleic acids containing the fragments of the SNVs are used as primers on the assembled sequences, they are preserved during amplification and can be detected. |
priorityDate | 2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 204.