http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105237473-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-85 |
filingDate | 2015-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105237473-B |
titleOfInvention | The 4,5,6 multifunctional amino nicotinic acid nitrile derivatives of dough 2 and preparation method |
abstract | A kind of 4,5,6 multifunctional amino nicotinic acid nitrile derivatives of dough 2, by under the conditions of organic solvent and alkali, with 2(1 aryl ethylidene)Malononitrile or 2(1 t butylethylidene)Malononitrile and alkene azide compounds are raw material, are generated after heating response.Provided by the invention 4,5, the 6 multifunctional amino nicotinic acid nitrile derivative synthesizing process of dough 2 are reasonable in design, and raw material is simple and easy to get, easy to operate, and reaction condition is easily achieved, and the reaction time is short, and yield is high, realizes economical and efficient purpose.4 prepared by the present invention, 5, the 6 multifunctional amino cigarette nitrile compounds of dough 2 have certain extracorporeal suppression tumor cell activity, can be used as antitumor lead compound.General structure is as follows: 。 |
priorityDate | 2015-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.