http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105232539-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 |
| filingDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105232539-B |
| titleOfInvention | Two breeds of horses bitterroot source organism alkali is used as the application for preparing anti-inflammatory drug |
| abstract | Two breeds of horses bitterroot source organism alkali is as the application for preparing anti-inflammatory drug or health products, and described two purslane source organism alkali are oleracimine and oleracone.The anti-inflammatory refers to suppress the inflammation caused by the excessive inflammatory cytokine of macrophage release or inflammatory mediator.The present invention is tested by the suppression to LPS inducing mouse macrophage RAW264.7 inflammatory reactions, shows that purslane source oleracimine and oleracone has suppression inflammatory factor IL 6, TNF α and suppresses inflammatory mediator NO, PGE 2 Effect, detected by Western blot and real-time fluorescence quantitative PCR show that oleracimine is inhibited to the albumen of iNOS, COX 2 and gene expression, and valid certificates two breeds of horses bitterroot source organism alkali has effects that anti-inflammatory.To sum up, purslane source organism alkali oleracimine and oleracone have good anti-inflammatory activity, can be used to prepare anti-inflammatory activity medicine as lead compound, to prevent or treat by NO, IL 6, TNF α and PGE 2 Inflammation caused by excess. |
| priorityDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.