http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105218679-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
| filingDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105218679-B |
| titleOfInvention | Human metapneumovirus multi-epitope antigen and its application |
| abstract | The present invention relates to human metapneumovirus multi-epitope antigen and its application, the human metapneumovirus multi-epitope antigen is combined by B cell epitope, Th cell epitopes, CTL cell epitope sequences, above-mentioned all types of epitope sequences are linked together by series system, and with connexon.The present invention also provides preparation, series connection and the expression of the human metapneumovirus B cell epitope, CTL cell epitopes and Th cell epitope genetic fragments, prepares human metapneumovirus multi-epitope antigen, and it is immune horizontal with humoral immune response to evaluate its active cell.Shown by evaluation experimental, the human metapneumovirus multi-epitope antigen of the present invention both can active cell it is immune in CTL it is immune and Th is immunized, also humoral immunity can be activated, experiment in vitro has certain neutralization to hMPV, it can be used for the exploitation of epiposition vaccine, establish amynologic diagnostic method, the immunization therapy that ailments epidemiological research and hMPV infect etc.. |
| priorityDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.