| abstract |
The invention provides a preparation method of a drug for treating lung cancer, specifically, the method uses 5-(3-morpholinopropoxy)-6-methoxyisatin (II) as a raw material, through oxidation, Substitution, chlorination and substitution to synthesize the target product (I). The method has the advantages of short synthetic route, simple experimental operation, environmental friendliness, high atom economy, good yield effect, etc., so it is suitable for industrial production. |