http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105213335-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 |
filingDate | 2015-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105213335-B |
titleOfInvention | Glipizide tablet as well as preparation method and application thereof |
abstract | The invention discloses a glipizide tablet as well as a preparation method and an application thereof. The glipizide tablet comprises the following components in percentage by weight: 1-5% of glipizide with the particle diameter D50 being 50-100 micrometers, 1-10% of a solubilizer, 50-90% of a filler, 5-15% of a disintegrating agent, 0.1-5% of a lubricant, and a suitable amount of 2-15% adhesive, wherein glipizide is preferably glipizide with the particle diameter D50 being 50-75 micrometers. According to the invention, the active ingredient glipizide is micronized, so that the particle diameter of the bulk drug is reduced, meanwhile, the solubilizer is added to be matched with glipizide, so that the drug release rate is increased, further, the bioavailability is improved, and the quality of the product is improved. |
priorityDate | 2015-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 120.