| abstract |
Compounds of general formula (I) or stereoisomers or pharmaceutically acceptable salts thereof are described herein. Such compounds have activity as SHIP1 modulators and are therefore useful in the treatment of any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulation. Compositions comprising a compound of general formula (I) in combination with a pharmaceutically acceptable carrier or diluent are also disclosed, as are methods of SHIP1 modulation by administering such compounds to an animal in need thereof. wherein R 1 , R 2 , R 3 , R 4 a , R 4b , R 5 , R 6 and R 7 are as defined herein. |