http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105200073-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| filingDate | 2010-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105200073-B |
| titleOfInvention | Human tumor necrosis factor receptor-Fc fusion and its product albumen |
| abstract | The invention discloses a kind of new recombined human TNFR75-Fc fusion, the gene contains sequence described in SEQ ID NO:3, which can significantly improve fusion protein expression；The present invention also provides a kind of recombinant vector pCI-gs-TNFR75-Fc simultaneously；During Fusion gene construction, 18 base complementrities that 18 bases and human IgG1 Fc genetic fragment 5 ' are held are introduced in 3 ' the end primers of TNFR75；The preparation method of Fc sections of genetic fragments of human soluble TNFRcDNA and human IgG1's heavy chain constant region in the screening technique and MSX concentration of cell strain, SEQ ID NO:3 sequence is improved simultaneously, finally improves fusion protein expression. |
| priorityDate | 2010-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 239.