http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105198833-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-64 |
| filingDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105198833-B |
| titleOfInvention | The synthesis technique of the formaldehyde of benzothiazole 2 |
| abstract | The present invention relates to a kind of synthesis technique of the formaldehyde of benzothiazole 2, comprise the following steps：Step one, benzothiazole, methanol, oxidant, phosphorus-containing catalyst are heated and stirred in closed reaction vessel and is reacted, the oxidant is potassium peroxydisulfate or sodium peroxydisulfate or the mixture of the two, filtering, filtrate decompression is concentrated, with acetone recrystallization, the benzothiazole dimethylacetal of solid 2 is obtained；Step 2,2 benzothiazole dimethylacetals are added in organic solvent DMF, acid catalyst is added and is reacted, is concentrated under reduced pressure, recrystallisation from isopropanol obtains the benzothiazole formaldehyde of white solid 2.The present invention has effectively facilitated the combined coefficient of the benzothiazole dimethylacetal of intermediate 2 using phosphorus-containing catalyst, and raw material is easy to get, and cost is low, step is simple, it is easy to operate, be conducive to the later stage further to synthesize the formaldehyde of benzothiazole 2, it is adaptable to the industrial extensive synthesis formaldehyde of benzothiazole 2. |
| priorityDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.