http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105198819-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-12 |
| filingDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105198819-B |
| titleOfInvention | The synthesis technique of the formaldehyde of benzimidazole 2 |
| abstract | The present invention relates to a kind of synthesis technique of the formaldehyde of benzimidazole 2, comprise the following steps：Using hydroxyapatite powder as catalyst, using 46 58 DEG C of hot water as solvent, reacted using o-phenylenediamine and glyoxalic acid as raw material, the mol ratio of the o-phenylenediamine and glyoxalic acid is 1:(1~1.2), reaction time are 2 10 hours, and reaction temperature is 46 58 DEG C, after reaction terminates, filters while hot, filtrate is cooled into 0~4 DEG C, there is white crystals precipitation, and filtering is crystallized, and is dried, is produced the formaldehyde of benzimidazole 2.The raw material and catalyst that synthetic method provided by the invention uses easily obtain, and cost is low；100 DEG C are not needed in operating procedure, 46 58 DEG C of reaction condition is relatively mild；Post processing is filtered, cooled down, refiltering and can obtain the formaldehyde of target product benzimidazole 2, simple to operate, therefore, suitable for the industrial formaldehyde of extensive synthesizing benzimidazole 2. |
| priorityDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.