http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105177047-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate | 2015-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105177047-B |
| titleOfInvention | Carry HPV 16 saltant type E7m94The recombined glandulae correlation viral vectors and its construction method of antigen gene and application |
| abstract | A kind of carrying HPV 16 E7 of the invention m94 The recombined glandulae correlation viral vectors and its construction method of antigen gene, it by the HPV-16 E7 gene mutation of the HPV 16 with oncogenicity is the HPV-16 E7 gene without oncogenicity to be, then by this be mutated after gene insertion rejected in the gland relevant viral vector of structural gene and obtained.The saltant type antigen gene that the recombinant adeno-associated virus of the present invention can be carried is conveyed into monocytic dendritic cell shape cell line, is used for the effector cell of stimulating immune system.It is demonstrated experimentally that the CTL induced by the DC that recombinant adeno-associated virus of the present invention infects can effectively suppress the growth of HPV 16E7 positive cells or kill the positive cells of HPV 16E7.The recombined glandulae correlation viral vectors or its Related product, which can be used for preparing treatment HPV 16, to be infected and its related antineoplastic. |
| priorityDate | 2014-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 184.