http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105177023-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 |
filingDate | 2014-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105177023-B |
titleOfInvention | Photosensitive degradant desVVD with stability regulated by blue light in eukaryotic cell |
abstract | The invention provides a photosensitive degradant desVVD with stability regulated by blue light in eukaryotic cells, a coding gene of the photosensitive degradant desVVD and a recombinant plasmid vector containing the coding gene. The invention provides a method for preparing a photosensitive degradant desVVD or a mutant thereof by using the recombinant plasmid vector, and also provides a fusion protein containing a target protein fused with the photosensitive degradant desVVD. The stability of the photosensitive degradant desVVD and the fusion protein fused with the degradant in eukaryotic cells is regulated and controlled by blue light. The present invention provides methods for controlling or altering the protein level of a target protein in a host cell via blue light. The method has the advantages of large change range, high blue light sensitivity, short action time, strong recoverability, small cytotoxicity and the like. |
priorityDate | 2014-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.