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filingDate 2014-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_440ff462dfca06ca80649398f331a6a7
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publicationDate 2015-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105177023-A
titleOfInvention Photosensitive degradable factor desVVD having stability regulated and controlled by blue ray in eukaryotic cells
abstract The invention provides a photosensitive degradable factor desVVD having the stability regulated and controlled by blue ray in eukaryotic cells, an encoding gene of the photosensitive degradable factor desVVD, and a recombinant plasmid vector containing the encoding gene. The invention provides a method for preparing the photosensitive degradable factor desVVD or a mutant thereof with the recombinant plasmid vector, and also provides a fusion protein comprising a target protein fused with the photosensitive degradable factor desVVD. The stability of the photosensitive degradable factor desVVD and the fusion protein fused with the degradation factor in the eukaryotic cells is regulated and controlled by the blue ray. The invention provides a method for controlling or changing the protein level of the target protein in a host cell by the blue ray. The method has the advantages of large change amplitude, high blue ray sensitivity, short action time, strong recoverability, small cell toxicity and the like.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113234686-A
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priorityDate 2014-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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