http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105169474-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
| filingDate | 2015-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105169474-B |
| titleOfInvention | Polypeptide material capable of carrying out self-assembly to form hydrogel under neutral pH condition and applications thereof |
| abstract | The invention provides a polypeptide material capable of carrying out self-assembly to form hydrogel under a neutral pH condition. The polypeptide material is prepared by the following steps: grafting a plurality of acidic amino acids and a plurality of alkaline amino acids to a RADA16-I sequence so as to form two short peptides with opposite charges, and mixing to carry out self-assembly to form the polypeptide material of hydrogel. The provided polypeptide material can carry out self-assembly in a neutral pH condition at a room temperature (similar to human physiological conditions) to form three-dimensional porous nano fiber hydrogel. The prepared material has a better biocompatibility, can be applied to in-situ cell/active cell loading and in-vivo in-situ injection, and has a wide application prospect and a high clinical application value in the fields such as three-dimensional cell cultivation, biological scaffold material used in tissue engineering, drug carriers, and the like. |
| priorityDate | 2015-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.